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Selected references on detection of TSEs and infectious prions by RT-QuIC using recombinant PrPs

 

Cerebrospinal fluid real-time quaking-induced conversion is a robust and reliable test for sporadic creutzfeldt-jakob disease: An international study. McGuire LI, Poleggi A, Poggiolini I, Suardi S, Grznarova K, Shi S, de Vil B, Sarros S, Satoh K, Cheng K, Cramm M, Fairfoul G, Schmitz M, Zerr I, Cras P, Equestre M, Tagliavini F, Atarashi R, Knox D, Collins S, Haïk S, Parchi P, Pocchiari M, Green A. Ann Neurol. 2016 Jul;80(1):160-5. PMID: 27130376. [PDF]

Factors that improve RT-QuIC detection of prion seeding activity. Orrú CD, Hughson AG, Groveman BR, Campbell KJ, Anson KJ, Manco M, Kraus A, Caughey B. Viruses. 2016 May 23; 8(5). PMID: 27223300. [PDF]

Real-time quaking-induced conversion analysis for the diagnosis of sporadic Creutzfeldt-Jakob disease in Korea. Park J-H, Choi Y-G, Lee Y-J, Park S-J, Choi H-S, Choi K-C, Choi E-K, Kim Y-S. J Clin Neurol. 2016. [PDF]

Bank vole prion protein as an apparently universal substrate for RT-QuIC-based detection and discrimination of prion strains. Orrú CD, Groveman BR, Raymond LD, Hughson AG, Nonno R, Zou W, Ghetti B, Gambetti P, Caughey B. PLoS Pathogens. 2015 Jun 18;11(6):e1004983. [PDF]

Detection of chronic wasting disease in the lymph nodes of free-ranging cervids by Real-Time Quaking-Induced Conversion. Haley NJ, Carver S, Hoon-Hanks LL, Henderson DM, Davenport KA, Bunting E, Gray S, Trindle B, Galeota J, LeVan I, Dubovos T, Shelton P, Hoover EA. J Clin Microbiol. 2014 Sep;52(9):3237-43. [PDF]

A test for Creutzfeldt-Jakob disease using nasal brushings. Orrú CD, Bongianni M, Tonoli G, Ferrari S, Hughson AG, Bradley MS, Groveman R, Fiorini M, Pocchiari M, Monaco S, Caughey B, Zanusso G. N Engl J Med. 2014 Nov 6;371(19):1842. [PDF]

Prion-seeding activity in cerebrospinal fluid of deer with chronic wasting disease. Haley NJ, Van de Motter A, Carver S, Henderson D, Davenport K, Seelig DM, Mathiason C, Hoover E. PLoS One. 2013 Nov 25;8(11):e81488. [PDF]

In vitro detection of prionemia in TSE-infected cervids and hamsters. Elder AM, Henderson DM, Nalls AV, Wilham JM, Caughey BW, Hoover EA, Kincaid AE, Bartz JC, Mathiason CK. PLoS One. 2013 Nov 1;8(11):e80203. [PDF]

Rapid antemortem detection of CWD prions in deer saliva. Henderson DM, Manca M, Haley NJ, Denkers ND, Nalls AV, Mathiason CK, Caughey B, Hoover EA. PLoS One. 2013 Sep 11;8(9):e74377. [PDF]

Establishing quantitative real-time quaking-induced conversion (qRT-QuIC) for highly sensitive detection and quantification of PrPSc in prion-infected tissues. Shi S, Mitteregger-Kretzschmar G, Giese A, Kretzschmar HA. Acta Neuropathol Commun. 2013 Aug 2;1(1):44. [PDF]

Early detection of chronic wasting disease prions in urine of pre-symptomatic deer by real-time quaking-induced conversion assay. John TR, Schatzl HM, Gilch S. Prion. 2013 May-Jun;7(3):253-8. [PDF]

Real-time quaking-induced conversion: a highly sensitive assay for prion detection. Atarashi R, Sano K, Satoh K, Nishida N. Prion. 2011 Jul-Sep;5(3):150-3. [PDF]

Prion disease blood test using immunoprecipitation and improved quaking-induced conversion. Orrú CD, Wilham JM, Raymond LD, Kuhn F, Schroeder B, Raeber AJ, Caughey B. mBio. 2011 May 10;2(3):e00078-11. [PDF]

Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays. Wilham JM, Orrú CD, Bessen RA, Atarashi R, Sano K, Race B, Meade-White KD, Taubner LM, Timmes A, Caughey B. PLoS Pathog. 2010 Dec 2;6(12):e1001217. [PDF]


 

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